教師成員

基本資料表

趙偉廷
32447(office)、32448(lab)
wtchao@thu.edu.tw
04-23590296
https://celllab.thu.edu.tw/
趙偉廷

教師

專任教師生醫組
副教授
細胞生物學， 癌症生物學，組織學，生物產業講堂，醫藥化學綜論
大腸癌及乳癌細胞群體轉移分子機制，細胞胞囊運送系統及藥物抗藥性，腫瘤細胞藥物配對及人工智慧系統
年度論文名稱
2020Single-Cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer
2020Application of trastuzumab emtansine in HER-2–positive and KRAS/BRAF-mutated colon cancer cells
2019The Roles Of Angiogenesis And Cancer Stem Cells In Sorafenib Drug Resistance In Hepatocellular Carcinoma
2019Cancer Metastasis: A Therapeutic Target
2018The Prognostic Value of Cytokeratin and Sal-Like Protein 4 Expression in Hepatocellular Carcinoma and Intra-Hepatic Cholangiocarcinoma in Taiwan.
2018Escin induces apoptosis in human bladder cancer cells: An in vitro and in vivo study.
2017Plectin deficiency in liver cancer cells promotes cell migration and sensitivity to sorafenib treatment
2017Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration
2017Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle-Related Transcription and Attenuated Androgen Response
2017Metformin-induced caveolin-1 expression promotes T-DM1 drug efficacy in breast cancer cells
2016High throughput cytotoxicity screening of anti-HER2 immunotoxins conjugated with antibody fragments from phage-displayed synthetic antibody libraries
2016Cell Pleomorphism and Cytoskeleton Disorganization in Human Liver Cancer
2016Rab11 collaborates E-cadherin to promote collective cell migration and indicates a poor prognosis in colorectal carcinoma
2016Biocompatible 3D SERS substrate for trace detection of amino acids and melamine
2015Caveolin-1 dependent endocytosis enhances the chemosensitivity of HER-2 positive breast cancer cells to trastuzumab emtansine (T-DM1)
2015Oncogenic roles of carbonic anhydrase 8 in human osteosarcoma cells
2014Rab11 regulates E-cadherin expression and induces cell transformation in colorectal carcinoma
2014Cell cycle arrest and cell survival induce reverse trends of cardiolipin remodeling.
2014Hypermethylation of the TGF-beta target, ABCA1 is associated with poor prognosis in ovarian cancer patients
2014Transient knockdown-mediated deficiency in plectin alters hepatocellular motility in association with activated FAK and Rac1-GTPase
2014Hypoacetylation in association with histone 3 modulation in human hepatocellular carcinoma
2013Anti-metastatic activity of biologically synthesized gold nanoparticles on human fibrosarcoma cell line HT-1080
2013Anticancer activities of an antimicrobial peptide derivative of Ixosin-B amide.
2012Design, Synthesis, and Evaluation of Fluorescent Cell-penetrating Peptidic Antagonists of Grb2 SH2 for Targeting MCF-7 Breast Cancer Cells
2011Cytokeratin 18-mediated disorganization of intermediate filaments is induced by degradation of plectin in human liver cells
2011Plectin deficiency on cytoskeletal disorganization and transformation of human liver cells in vitro.
2010Synemin down-regulation in human hepatocellular carcinoma does not destabilize cytoskeletons in vivo
2010Type I PIPK-alpha regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation.
2010Type I PIP kinase beta regulates focal adhesion disassembly by promoting beta1 integrin endocytosis
2009Focal adhesion disassembly requires clathrin-dependent endocytosis of integrins
2008Degradation of Plectin with Modulation of Cytokeratin 18 in Human Liver Cells during Staurosporine Induced Apoptosis
2008The influence of plectin deficiency on stability of cytokeratin18 in hepatocellular carcinoma
2005Cellular localization and interaction of ABCA1 and caveolin-1 in aortic endothelial cells after HDL incubation
2004Effect of EGCg, major component of green tea, on the expression of Ets-1, c-Fos, and c-Jun during angiogenesis in vitro
2003Use of gain-of-function Study to delineate the roles of crumbs in drosophila eye development
2003Visualizing caveolin-1 and HDL in cholesterol-loaded aortic endothelial cells
年度計畫名稱參與人計畫期間補助/委託或合作機構
2019科普活動：以火星為任務為主題進行全國性科學競賽 （主題一）趙偉廷2019-08~2019-12科技部
2019探討Src在調節細胞間連著分子及細胞貼附分子的機制對大腸癌細胞進行群體移行的影響趙偉廷2019-08~2020-07科技部
2018紅血球生成素對大腸癌細胞群體細胞移行的影響趙偉廷2019-01~2019-12台中榮總與東海大學合作研究計畫
2018給予苦瓜胜肽調控「低劑量STZ誘導仿高血糖大鼠」之高血糖現象的效益評估趙偉廷2018-08~2019-09綠茵生技股份有限公司
2017紅血球生成素的使用在誘發大腸癌症幹細胞轉移時所扮演的角色趙偉廷2018-01~2018-12台中榮總與東海大學合作研究計畫
2016Niclosamide 結合自嗜抑制劑(Chloroquine)於人類移行細胞癌之抗癌機轉研究趙偉廷2017-01~2017-12台中榮總與東海大學合作研究計畫
2015評估合併Escin與Cisplatin在膀胱癌細胞之抗癌效果及作用機制趙偉廷2016-01~2016-12台中榮總與東海大學合作研究計畫
2015新穎的葡萄糖代謝機制在大腸癌上的治療策略 (1/3)趙偉廷2015-08~2016-07科技部
2015動物組織學課程之生物醫材產業生物相容性測試人才培育計畫 趙偉廷2015-02~2015-06東海大學
2015高效能平台快速鑑定醫療用抗體之抗原決定位於次奈米解析度 趙偉廷2015-01~2015-12中央研究院
2015使用斑點追蹤心臟超音波評估miR-33拮抗劑提升HDL，對白兔心肌之影響 趙偉廷2015-01~2015-12台中榮總東海大學聯合計畫
2014ISO109932動物生物相容性試驗 趙偉廷2014-08~2014-12財團法人塑膠工業研究中心
2014醫療器材生物性產品應用於天竺鼠敏感性測試及紐西蘭兔皮膚(皮下、眼)刺激性測試、熱原試驗及小鼠系統急性毒性試驗 趙偉廷2014-03~2014-08財團法人塑膠工業研究中心
2014使用斑點追蹤心臟超音波評估心肌缺氧白兔，使用Cav-1蛋白治療前後心肌形變與形變率 趙偉廷2014-01~2014-12台中榮總東海大學聯合計畫
2014E-cadherin在大腸癌黏膜組織細胞中的大量表現與細胞內胞囊運送失衡的機制探討趙偉廷2013-08~2014-07科技部
2013奈米氧化鐵粒子與細胞毒性關聯性及可能機轉研究 趙偉廷2013-01~2013-12衛福部
2012國產化鈦金屬血管夾開發評估 趙偉廷2012-08~2012-12財團法人精密機械研究中心
2013細胞移行快速檢測晶片的研發 趙偉廷2012-07~2013-02科技部
學校名稱國別系所學位起迄年月
東海大學生物學研究所博士1999-08~2003-07
東海大學生物學研究所碩士1997-08~1999-07
東海大學生物系學士1993-08~1997-07
服務機關名稱單位職務期間
東海大學生命科學系助理教授2011-08~2015-01
美國貝勒醫學院分子生理系博士後研究員2004-05~2011-06
東海大學生命科學系博士後研究員2003-08~2004-04